What is ozone?
Ozone is also known as activated oxygen. Oxygen is O2 and Ozone is O3, meaning it contains three oxygen molecules instead of two. After a short time, that third molecule will break off and start the work of ozone therapy.
Ozone safety?
The largest safety study was conducted in 1980 by Jacobs (1982) for the German Medical Society for Ozone Therapy. She surveyed 2815 known European ozone therapists with a 25% response rate. The report tallied 384,775 patients and 5,579,238 ozone treatments. The risk of adverse incidents was only 0.7 per 100,000 treatments, often related to improper administration. Pediatrician Robert Mayer (1983) reported on 3000 administrations (including intrathecal ozone gas for meningitis), most in children. Mayer found ozone “without any side effects or toxicity noted.” Robins (2018) reported performing over 300,000 ozone treatments utilizing direct intravenous gas (DIV) with no lasting ill effects other than vein irritation with this particular method. Rowen (2016) conducted and presented a survey of those he has trained in a delivery method called “hyperbaric ozone.” No significant adverse problems reported in 30,000 + observed treatments. Ozone therapy appears to be one of the safest, if not the safest, treatment modalities ever known
Millions of patients treated so far from the thousands of physicians correctly practicing OT world widely in the last 40 years demonstrate the safety of this simple and cost-effective regenerative medicine tool. The promising therapeutic implications also for the current COVID-19 emergency are a further stimulus to the standardization of this therapeutic resource with multiple application specificities.
https://pubmed.ncbi.nlm.nih.gov/33176412/
Peer Reviewed Articles: safety and efficacy of ozone
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674660/
Link to entire article pdf
Conclusions
O3 therapy can alter the natural history of several disease and disorders, with potentially many more yet untested. A plethora of laboratory studies have provided evidence of O3's antioxidant capabilities, as well as vascular, hematological, and immune system modulations. This evidence has been further substantiated in clinical trials with O3 therapy being useful in the cardiovascular, subcutaneous tissue, peripheral vascular disease, neurological, head and neck, orthopedic, gastrointestinal, and genitourinary pathologies. O3therapy has proven especially beneficial in the diabetic foot, ischemic wounds, and peripheral vascular disease, areas in which O3 use is most prevalent. Upcoming laboratory and translational research should begin to develop protocols for O3-AHT in attempts to establish a dose-response relationship as it has demonstrated high utility in a myriad of pathologies at varying concentrations. Despite the presently compelling evidence, future studies should include more double-blind, randomized clinical trials with greater sample sizes, determination of longevity in benefits produced, as well as methods of measurements and analysis.